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Pinning Down the Transcription: A Role for Peptidyl-Prolyl cis-trans Isomerase Pin1 in Gene Expression

Pin1 is a peptidyl-prolyl cis-trans isomerase that specifically binds to a phosphorylated serine or threonine residue preceding a proline (pSer/Thr-Pro) motif and catalyzes the cis-trans isomerization of proline imidic peptide bond, resulting in conformational change of its substrates. Pin1 regulate...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Hu, Xiangming, Chen, Lin-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100383/
https://ncbi.nlm.nih.gov/pubmed/32266261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00179
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