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Distinguishing crystal-like amyloid fibrils and glass-like amorphous aggregates from their kinetics of formation

Amyloid fibrils and amorphous aggregates are two types of aberrant aggregates associated with protein misfolding diseases. Although they differ in morphology, the two forms are often treated indiscriminately. β(2)-microglobulin (β2m), a protein responsible for dialysis-related amyloidosis, forms amy...

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Main Authors: Yoshimura, Yuichi, Lin, Yuxi, Yagi, Hisashi, Lee, Young-Ho, Kitayama, Hiroki, Sakurai, Kazumasa, So, Masatomo, Ogi, Hirotsugu, Naiki, Hironobu, Goto, Yuji
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437889/
https://ncbi.nlm.nih.gov/pubmed/22908252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208228109
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