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Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy

It is challenging to investigate the structure and dynamics of amyloid fibrils at the residue and atomic resolution because of their high molecular weight and heterogeneous properties. Here, we used solution nuclear magnetic resonance (NMR) spectroscopy to characterize the conformation and flexibili...

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Dettagli Bibliografici
Autori principali: Yoshimura, Yuichi, Sakurai, Kazumasa, Lee, Young-Ho, Ikegami, Takahisa, Chatani, Eri, Naiki, Hironobu, Goto, Yuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009402/
https://ncbi.nlm.nih.gov/pubmed/20936689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.515
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