Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy
Amyloid is the result of an anomalous protein and peptide aggregation, leading to the formation of insoluble fibril deposits. At present, 18 human diseases have been associated with amyloid deposits—e.g., Alzheimer's disease and Prion-transmissible Spongiform Encephalopathies. The molecular structur...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072564/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132098999 |
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