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Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy
Amyloid is the result of an anomalous protein and peptide aggregation, leading to the formation of insoluble fibril deposits. At present, 18 human diseases have been associated with amyloid deposits—e.g., Alzheimer's disease and Prion-transmissible Spongiform Encephalopathies. The molecular str...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC124346/ https://ncbi.nlm.nih.gov/pubmed/12072564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.132098999 |
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