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The apical stem–loop of the hepatitis B virus encapsidation signal folds into a stable tri–loop with two underlying pyrimidine bulges
Reverse transcription of hepatitis B virus (HBV) pregenomic RNA is essential for virus replication. In the first step of this process, HBV reverse transcriptase binds to the highly conserved encapsidation signal, epsilon (ε), situated near the 5′ end of the pregenome. ε has been predicted to form a...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2002
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135823/ https://ncbi.nlm.nih.gov/pubmed/12409471 |
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