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The apical stem–loop of the hepatitis B virus encapsidation signal folds into a stable tri–loop with two underlying pyrimidine bulges

Reverse transcription of hepatitis B virus (HBV) pregenomic RNA is essential for virus replication. In the first step of this process, HBV reverse transcriptase binds to the highly conserved encapsidation signal, epsilon (ε), situated near the 5′ end of the pregenome. ε has been predicted to form a...

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Udgivet i:Nucleic Acids Res
Principais autores: Flodell, Sara, Schleucher, Jürgen, Cromsigt, Jenny, Ippel, Hans, Kidd-Ljunggren, Karin, Wijmenga, Sybren
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12409471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf603
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