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Probing solvent accessibility of amyloid fibrils by solution NMR spectroscopy

Amyloid is the result of an anomalous protein and peptide aggregation, leading to the formation of insoluble fibril deposits. At present, 18 human diseases have been associated with amyloid deposits—e.g., Alzheimer's disease and Prion-transmissible Spongiform Encephalopathies. The molecular structur...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Ippel, Johannes H., Olofsson, Anders, Schleucher, Jürgen, Lundgren, Erik, Wijmenga, Sybren S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12072564/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.132098999
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