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Destruction of Amyloid Fibrils of Keratoepithelin Peptides by Laser Irradiation Coupled with Amyloid-specific Thioflavin T

Mutations in keratoepithelin are associated with blinding ocular diseases, including lattice corneal dystrophy type 1 and granular corneal dystrophy type 2. These diseases are characterized by deposits of amyloid fibrils and/or granular non-amyloid aggregates in the cornea. Removing the deposits in...

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Bibliographische Detailangaben
Hauptverfasser: Ozawa, Daisaku, Kaji, Yuichi, Yagi, Hisashi, Sakurai, Kazumasa, Kawakami, Toru, Naiki, Hironobu, Goto, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060536/
https://ncbi.nlm.nih.gov/pubmed/21300800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.222901
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