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Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy

It is challenging to investigate the structure and dynamics of amyloid fibrils at the residue and atomic resolution because of their high molecular weight and heterogeneous properties. Here, we used solution nuclear magnetic resonance (NMR) spectroscopy to characterize the conformation and flexibili...

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Detalhes bibliográficos
Main Authors: Yoshimura, Yuichi, Sakurai, Kazumasa, Lee, Young-Ho, Ikegami, Takahisa, Chatani, Eri, Naiki, Hironobu, Goto, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009402/
https://ncbi.nlm.nih.gov/pubmed/20936689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.515
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