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Direct observation of minimum-sized amyloid fibrils using solution NMR spectroscopy
It is challenging to investigate the structure and dynamics of amyloid fibrils at the residue and atomic resolution because of their high molecular weight and heterogeneous properties. Here, we used solution nuclear magnetic resonance (NMR) spectroscopy to characterize the conformation and flexibili...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3009402/ https://ncbi.nlm.nih.gov/pubmed/20936689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.515 |
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