Thioredoxin Reductase Inhibition Elicits Nrf2-Mediated Responses in Clara Cells: Implications for Oxidant-Induced Lung Injury

Aims: Pulmonary oxygen toxicity contributes to lung injury in newborn and adult humans. We previously reported that thioredoxin reductase (TrxR1) inhibition with aurothioglucose (ATG) attenuates hyperoxic lung injury in adult mice. The present studies tested the hypothesis that TrxR1 inhibition prot...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Locy, Morgan L., Rogers, Lynette K., Prigge, Justin R., Schmidt, Edward E., Arnér, Elias S.J., Tipple, Trent E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2012
Ämnen:
Original Research Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437047/
https://ncbi.nlm.nih.gov/pubmed/22607006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4377
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk