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PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice

Clinical trials in Parkinson’s disease have shown that transplants of embryonic mesencephalic dopamine neurons form new functional connections within the host striatum, but the therapeutic benefits have been highly variable. One obstacle has been poor survival and integration of grafted dopamine neu...

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Bibliografische gegevens
Hoofdauteurs: Zhang, YaJun, Granholm, Ann-Charlotte, Huh, Kyounghee, Shan, Lufei, Diaz-Ruiz, Oscar, Malik, Nasir, Olson, Lars, Hoffer, Barry J., Lupica, Carl R., Hoffman, Alexander F., Bäckman, Cristina M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437026/
https://ncbi.nlm.nih.gov/pubmed/22961549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws196
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