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PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice
Clinical trials in Parkinson’s disease have shown that transplants of embryonic mesencephalic dopamine neurons form new functional connections within the host striatum, but the therapeutic benefits have been highly variable. One obstacle has been poor survival and integration of grafted dopamine neu...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437026/ https://ncbi.nlm.nih.gov/pubmed/22961549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/aws196 |
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