Multimodal MRI Evaluation of the MitoPark Mouse Model of Parkinson’s Disease

The MitoPark mouse, a relatively new genetic model of Parkinson’s disease (PD), has a dopaminergic neuron-specific knock-out that inactivates the mitochondrial transcription factor A (Tfam), a protein essential for mitochondrial DNA expression and maintenance. This study used multimodal MRI to chara...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cong, Linlin, Muir, Eric R., Chen, Cang, Qian, Yusheng, Liu, Jingwei, Biju, K. C., Clark, Robert A., Li, Senlin, Duong, Timothy Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803323/
https://ncbi.nlm.nih.gov/pubmed/27003179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151884
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