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Altered glutamate release in the dorsal striatum of the MitoPark mouse model of Parkinson’s disease

Mitochondrial dysfunction has been implicated in the degeneration of dopamine (DA) neurons in Parkinson’s disease (PD). In addition, animal models of PD utilizing neurotoxins, such as 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, have shown that these toxins disrupt mitochondri...

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Publicado en:Brain Res
Autores principales: Farrand, Ariana Q., Gregory, Rebecca A., Bäckman, Cristina M., Helke, Kristi L., Boger, Heather A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5085862/
https://ncbi.nlm.nih.gov/pubmed/27659966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2016.09.025
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