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Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice

Glial cell line-derived neurotrophic factor (GDNF) helps protect dopaminergic neurons in the nigrostriatal tract. Although the cause of nigrostriatal degeneration is unknown, one theory is that excess glutamate from the subthalamic nucleus (STN) results in excitotoxic events in the substantia nigra...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurobiol Aging
Päätekijät: Farrand, Ariana Q, Gregory, Rebecca A, Scofield, Michael D, Helke, Kristi L, Boger, Heather A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346478/
https://ncbi.nlm.nih.gov/pubmed/25577412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.11.017
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