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Effects of aging on glutamate neurotransmission in the substantia nigra of Gdnf heterozygous mice

Glial cell line-derived neurotrophic factor (GDNF) helps protect dopaminergic neurons in the nigrostriatal tract. Although the cause of nigrostriatal degeneration is unknown, one theory is that excess glutamate from the subthalamic nucleus (STN) results in excitotoxic events in the substantia nigra...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Farrand, Ariana Q, Gregory, Rebecca A, Scofield, Michael D, Helke, Kristi L, Boger, Heather A
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346478/
https://ncbi.nlm.nih.gov/pubmed/25577412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.11.017
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