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Minocycline Restores Striatal Tyrosine Hydroxylase in GDNF Heterozygous Mice But Not in Methamphetamine-treated Mice
Inflammation, phospho-p38 MAP kinase activation, and a reduction in glial cell line-derived neurotrophic factor (GDNF) occur in Parkinson’s disease. Microglial activation in the substantia nigra and a tyrosine hydroxylase deficit in the striatum of 3-month-old GDNF heterozygous (GDNF(+/−)) mice were...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645227/ https://ncbi.nlm.nih.gov/pubmed/19110059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.11.013 |
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