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An Intrastriatal Brain-Derived Neurotrophic Factor Infusion Restores Striatal Gene Expression in Bdnf Heterozygous Mice
Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington’s disease. In young Bdnf heterozygous ((+/−)) mice, striatal medium spiny neurons express less preprodynorphin...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104292/ https://ncbi.nlm.nih.gov/pubmed/20938680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-010-0282-9 |
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