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An Intrastriatal Brain-Derived Neurotrophic Factor Infusion Restores Striatal Gene Expression in Bdnf Heterozygous Mice

Reduction in the amount of brain-derived neurotrophic factor (BDNF) in corticostriatal afferents is thought to contribute to the vulnerability of medium spiny striatal neurons in Huntington’s disease. In young Bdnf heterozygous ((+/−)) mice, striatal medium spiny neurons express less preprodynorphin...

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Detalhes bibliográficos
Main Authors: Saylor, Alicia J., McGinty, Jacqueline F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104292/
https://ncbi.nlm.nih.gov/pubmed/20938680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00429-010-0282-9
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