The E3 Ubiquitin Ligase Protein Associated with Myc (Pam) Regulates Mammalian/Mechanistic Target of Rapamycin Complex 1 (mTORC1) Signaling in Vivo through N- and C-terminal Domains

Pam and its homologs (the PHR protein family) are large E3 ubiquitin ligases that function to regulate synapse formation and growth in mammals, zebrafish, Drosophila, and Caenorhabditis elegans. Phr1-deficient mouse models (Phr1(Δ8,9) and Phr1(Magellan), with deletions in the N-terminal putative gua...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Han, Sangyeul, Kim, Sun, Bahl, Samira, Li, Lin, Burande, Clara F., Smith, Nicole, James, Marianne, Beauchamp, Roberta L., Bhide, Pradeep, DiAntonio, Aaron, Ramesh, Vijaya
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2012
Θέματα:
Signal Transduction
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436263/
https://ncbi.nlm.nih.gov/pubmed/22798074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.353987
Ετικέτες: Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!

Παρόμοια τεκμήρια