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Indole peroxygenase activity of indoleamine 2,3-dioxygenase

The heme enzyme indoleamine 2,3-dioxygenase (IDO) was found to catalyze the oxidation of indole by H(2)O(2), with generation of 2- and 3-oxoindole as the major products. This reaction occurred in the absence of O(2) and reducing agents and was not inhibited by superoxide dismutase or hydroxyl radica...

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Autori principali: Kuo, Hsin H., Mauk, A. Grant
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435167/
https://ncbi.nlm.nih.gov/pubmed/22891315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207191109
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