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Indole peroxygenase activity of indoleamine 2,3-dioxygenase
The heme enzyme indoleamine 2,3-dioxygenase (IDO) was found to catalyze the oxidation of indole by H(2)O(2), with generation of 2- and 3-oxoindole as the major products. This reaction occurred in the absence of O(2) and reducing agents and was not inhibited by superoxide dismutase or hydroxyl radica...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435167/ https://ncbi.nlm.nih.gov/pubmed/22891315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207191109 |
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