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NADH Oxidase Activity of Indoleamine 2,3-Dioxygenase

The heme enzyme indoleamine 2,3-dioxygenase (IDO) was found to oxidize NADH under aerobic conditions in the absence of other enzymes or reactants. This reaction led to the formation of the dioxygen adduct of IDO and supported the oxidation of Trp to N-formylkynurenine. Formation of the dioxygen addu...

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Detalhes bibliográficos
Main Authors: Rosell, Federico I., Kuo, Hsin H., Mauk, A. Grant
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190733/
https://ncbi.nlm.nih.gov/pubmed/21690092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.262139
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