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SUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity

Phosphorylation or SUMOylation of the kainate receptor (KAR) subunit GluK2 have both individually been shown to regulate KAR surface expression. However, it is unknown if phosphorylation and SUMOylation of GluK2 are important for activity-dependent KAR synaptic plasticity. Here, we show that PKC-med...

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Detalhes bibliográficos
Main Authors: Chamberlain, Sophie E L, González-González, Inmaculada M, Wilkinson, Kevin A, Konopacki, Filip A, Kantamneni, Sriharsha, Henley, Jeremy M, Mellor, Jack R
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435142/
https://ncbi.nlm.nih.gov/pubmed/22522402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3089
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