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Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3

Seizure protein 6 (SEZ6) is required for the development and maintenance of the nervous system, is a major substrate of the protease BACE1 and is linked to Alzheimer's disease (AD) and psychiatric disorders, but its molecular functions are not well understood. Here, we demonstrate that SEZ6 con...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Pigoni, Martina, Hsia, Hung‐En, Hartmann, Jana, Rudan Njavro, Jasenka, Shmueli, Merav D, Müller, Stephan A, Güner, Gökhan, Tüshaus, Johanna, Kuhn, Peer‐Hendrik, Kumar, Rohit, Gao, Pan, Tran, Mai Ly, Ramazanov, Bulat, Blank, Birgit, Hipgrave Ederveen, Agnes L, Von Blume, Julia, Mulle, Christophe, Gunnersen, Jenny M, Wuhrer, Manfred, Rammes, Gerhard, Busche, Marc Aurel, Koeglsperger, Thomas, Lichtenthaler, Stefan F
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396870/
https://ncbi.nlm.nih.gov/pubmed/32567721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103457
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