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SUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity

Phosphorylation or SUMOylation of the kainate receptor (KAR) subunit GluK2 have both individually been shown to regulate KAR surface expression. However, it is unknown if phosphorylation and SUMOylation of GluK2 are important for activity-dependent KAR synaptic plasticity. Here, we show that PKC-med...

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Autors principals: Chamberlain, Sophie E L, González-González, Inmaculada M, Wilkinson, Kevin A, Konopacki, Filip A, Kantamneni, Sriharsha, Henley, Jeremy M, Mellor, Jack R
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435142/
https://ncbi.nlm.nih.gov/pubmed/22522402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3089
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