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SUMOylation and phosphorylation of GluK2 regulate kainate receptor trafficking and synaptic plasticity

Phosphorylation or SUMOylation of the kainate receptor (KAR) subunit GluK2 have both individually been shown to regulate KAR surface expression. However, it is unknown if phosphorylation and SUMOylation of GluK2 are important for activity-dependent KAR synaptic plasticity. Here, we show that PKC-med...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chamberlain, Sophie E L, González-González, Inmaculada M, Wilkinson, Kevin A, Konopacki, Filip A, Kantamneni, Sriharsha, Henley, Jeremy M, Mellor, Jack R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435142/
https://ncbi.nlm.nih.gov/pubmed/22522402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3089
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