Agonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis

The surface expression and regulated endocytosis of kainate (KA) receptors (KARs) plays a critical role in neuronal function. PKC can modulate KAR trafficking, but the sites of action and molecular consequences have not been fully characterized. Small ubiquitin-like modifier (SUMO) modification of t...

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Main Authors: Konopacki, Filip A., Jaafari, Nadia, Rocca, Dan L., Wilkinson, Kevin A., Chamberlain, Sophie, Rubin, Philip, Kantamneni, Sriharsha, Mellor, Jack R., Henley, Jeremy M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2011
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241814/
https://ncbi.nlm.nih.gov/pubmed/22089239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111575108
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