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Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide

Temozolomide (TMZ) is standard chemotherapy for glioblastoma multiforme (GBM). Intratumoral hypoxia is common in GBM and may be associated with the development of TMZ resistance. Oxygen therapy has previously been reported to potentiate the effect of chemotherapy in cancer. In this study, we investi...

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Bibliografiske detaljer
Main Authors: Sun, Stella, Lee, Derek, Lee, Nikki P., Pu, Jenny K. S., Wong, Stanley T. S., Lui, W. M., Fung, C. F., Leung, Gilberto K. K.
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434886/
https://ncbi.nlm.nih.gov/pubmed/22763762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-012-0923-3
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