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Hyperoxia resensitizes chemoresistant human glioblastoma cells to temozolomide

Temozolomide (TMZ) is standard chemotherapy for glioblastoma multiforme (GBM). Intratumoral hypoxia is common in GBM and may be associated with the development of TMZ resistance. Oxygen therapy has previously been reported to potentiate the effect of chemotherapy in cancer. In this study, we investi...

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Detalhes bibliográficos
Main Authors: Sun, Stella, Lee, Derek, Lee, Nikki P., Pu, Jenny K. S., Wong, Stanley T. S., Lui, W. M., Fung, C. F., Leung, Gilberto K. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434886/
https://ncbi.nlm.nih.gov/pubmed/22763762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-012-0923-3
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