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IκB Kinase α Phosphorylation of TRAF4 Downregulates Innate Immune Signaling
Despite their homology, IκB kinase α (IKKα) and IKKβ have divergent roles in NF-κB signaling. IKKβ strongly activates NF-κB while IKKα can downregulate NF-κB under certain circumstances. Given this, identifying independent substrates for these kinases could help delineate their divergent roles. Pept...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434482/ https://ncbi.nlm.nih.gov/pubmed/22547678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00106-12 |
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