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IκB Kinase ε Phosphorylates TRAF2 To Promote Mammary Epithelial Cell Transformation
NF-κB transcription factors are central regulators of inflammation and when dysregulated contribute to malignant transformation. IκB kinase ε (IKKε; IKKi, encoded by IKBKE) is a breast oncogene that is amplified in 30% of breast cancers and drives transformation in an NF-κB-dependent manner. Here we...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497603/ https://ncbi.nlm.nih.gov/pubmed/23007157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00468-12 |
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