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Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKε promotes cell transformation

The non-canonical IKK family member IKKε is essential for regulating anti-viral signaling pathways and is a recently-discovered breast cancer oncoprotein. Although several IKKε targets have been described, direct IKKε substrates necessary for regulating cell transformation have not been identified....

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Detalhes bibliográficos
Main Authors: Hutti, Jessica E., Shen, Rhine R., Abbott, Derek W., Zhou, Alicia Y., Sprott, Kam M., Asara, John M., Hahn, William C., Cantley, Lewis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746958/
https://ncbi.nlm.nih.gov/pubmed/19481526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.031
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