The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism

IκB kinase ε (IKKε) is a key molecule at the crossroads of inflammation and cancer. Known to regulate cytokine secretion via NFκB and IRF3, the kinase is also a breast cancer oncogene, overexpressed in a variety of tumours. However, to what extent IKKε remodels cellular metabolism is currently unkno...

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Publicado no:EMBO Rep
Main Authors: Xu, Ruoyan, Jones, William, Wilcz‐Villega, Ewa, Costa, Ana SH, Rajeeve, Vinothini, Bentham, Robert B, Bryson, Kevin, Nagano, Ai, Yaman, Busra, Olendo Barasa, Sheila, Wang, Yewei, Chelala, Claude, Cutillas, Pedro, Szabadkai, Gyorgy, Frezza, Christian, Bianchi, Katiuscia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116048/
https://ncbi.nlm.nih.gov/pubmed/32783398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948260
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