Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway

During obesity, macrophages infiltrate the breast tissue leading to low‐grade chronic inflammation, a factor considered responsible for the higher risk of breast cancer associated with obesity. Here, we formally demonstrate that breast epithelial cells acquire malignant properties when exposed to me...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Wilcz‐Villega, Ewa, Carter, Edward, Ironside, Alastair, Xu, Ruoyan, Mataloni, Isabella, Holdsworth, Julie, Jones, William, Moreno Béjar, Rocío, Uhlik, Lukas, Bentham, Robert B, Godinho, Susana A, Dalli, Jesmond, Grose, Richard, Szabadkai, Gyorgy, Jones, Louise, Hodivala‐Dilke, Kairbaan, Bianchi, Katiuscia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005540/
https://ncbi.nlm.nih.gov/pubmed/31930708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910491
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