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Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε
IKKε and TBK1 are noncanonical IKK family members which regulate inflammatory signaling pathways and also play important roles in oncogenesis. However, few inhibitors of these kinases have been identified. While the substrate specificity of IKKε has recently been described, the substrate specificity...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408500/ https://ncbi.nlm.nih.gov/pubmed/22859992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041494 |
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