Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε

IKKε and TBK1 are noncanonical IKK family members which regulate inflammatory signaling pathways and also play important roles in oncogenesis. However, few inhibitors of these kinases have been identified. While the substrate specificity of IKKε has recently been described, the substrate specificity...

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書誌詳細
主要な著者: Hutti, Jessica E., Porter, Melissa A., Cheely, Adam W., Cantley, Lewis C., Wang, Xiaodong, Kireev, Dmitri, Baldwin, Albert S., Janzen, William P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408500/
https://ncbi.nlm.nih.gov/pubmed/22859992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041494
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