INGN 007, an oncolytic adenovirus vector, replicates in Syrian hamsters but not mice: comparison of biodistribution studies

Preclinical biodistribution studies with INGN 007, an oncolytic adenovirus (Ad) vector, supporting an early stage clinical trial were conducted in Syrian hamsters, which are permissive for Ad replication, and mice, which are a standard model for assessing toxicity and biodistribution of replication-...

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Bibliographic Details
Main Authors: Ying, B, Toth, K, Spencer, JF, Meyer, J, Tollefson, AE, Patra, D, Dhar, D, Shashkova, EV, Kuppuswamy, M, Doronin, K, Thomas, MA, Zumstein, LA, Wold, WSM, Lichtenstein, DL
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433952/
https://ncbi.nlm.nih.gov/pubmed/19197322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.6
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