Caricamento...
Characterization of TAE684 as a potent LRRK2 kinase inhibitor
Leucine-rich repeat kinase 2 (LRRK2) is linked to Parkinson’s disease and may represent an attractive therapeutic target. Here we report a 2,4-dianilino-5-chloro-pyrimidine, TAE684, a previously reported inhibitor of anaplastic lymphoma kinase (ALK), is also a potent inhibitor of LRRK2 kinase activi...
Salvato in:
| Autori principali: | , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433743/ https://ncbi.nlm.nih.gov/pubmed/22335897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.01.084 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|