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Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins

Shiga-like toxins and ricin are ribosome-inactivating proteins (RIPs) that are lethal to mammals and pose a global health threat. No clinical vaccines or therapeutics currently exist to protect against these RIPs. Two small molecules (Retro-1 and Retro-2) were discovered with high-throughput screeni...

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Sonraí Bibleagrafaíochta
Main Authors: Park, Jewn Giew, Kahn, Jennifer Nielsen, Tumer, Nilgun E., Pang, Yuan-Ping
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433688/
https://ncbi.nlm.nih.gov/pubmed/22953052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00631
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