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Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins

Ribosome-inactivating proteins (RIPs) are potent toxins that inactivate ribosomes by catalytically removing a specific adenine from the α-sarcin/ricin loop (SRL) of the large rRNA. Direct assays for measuring depurination activity and indirect assays for measuring the resulting translation inhibitio...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Zhou, Yijun, Li, Xiao-Ping, Kahn, Jennifer N., Tumer, Nilgun E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024586/
https://ncbi.nlm.nih.gov/pubmed/29899209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10060240
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