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Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins
Shiga-like toxins and ricin are ribosome-inactivating proteins (RIPs) that are lethal to mammals and pose a global health threat. No clinical vaccines or therapeutics currently exist to protect against these RIPs. Two small molecules (Retro-1 and Retro-2) were discovered with high-throughput screeni...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3433688/ https://ncbi.nlm.nih.gov/pubmed/22953052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00631 |
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