Loading...

Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice

In the present study, we used the GTP cyclohydrolase I-deficient mice, ie., hph-1 mice, to test the hypothesis that the loss of tetrahydrobiopterin (BH(4)) in cerebral microvessels causes endothelial nitric oxide synthase (eNOS) uncoupling resulting in increased superoxide anion production and inhib...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Santhanam, Anantha Vijay R, d'Uscio, Livius V., Smith, Leslie A, Katusic, Zvonimir S
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433644/
https://ncbi.nlm.nih.gov/pubmed/22784235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07872.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!