A carregar...
Stapled BH3 Peptides against MCL-1: Mechanism and Design Using Atomistic Simulations
Atomistic simulations of a set of stapled alpha helical peptides derived from the BH3 helix of MCL-1 (Stewart et al. (2010) Nat Chem Biol 6: 595–601) complexed to a fragment (residues 172–320) of MCL-1 revealed that the highest affinity is achieved when the staples engage the surface of MCL-1 as has...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3432064/ https://ncbi.nlm.nih.gov/pubmed/22952838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043985 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|