Serum Sclerostin Increases in Healthy Adult Men during Bed Rest

CONTEXT: Animal models and human studies suggest that osteocytes regulate the skeleton's response to mechanical unloading in part by an increase in sclerostin. However, few studies have reported changes in serum sclerostin in humans exposed to reduced mechanical loading. OBJECTIVE: We determine...

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Hlavní autoři: Spatz, J. M., Fields, E. E., Yu, E. W., Pajevic, P. Divieti, Bouxsein, M. L., Sibonga, J. D., Zwart, S. R., Smith, S. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
JCEM Online: Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431567/
https://ncbi.nlm.nih.gov/pubmed/22767636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-1579
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