Nalaganje...
Loss of Gsα in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity
The stimulatory subunit of G-protein, Gsα, acts as a secondary messenger of G-protein coupled receptors (GPCRs) that primarily activates cAMP-induced signaling. GPCRs, such as the parathyroid receptor (PTHR), are critical regulators of bone formation as shown by number of genetic manipulation studie...
Shranjeno v:
| izdano v: | Bone |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6207374/ https://ncbi.nlm.nih.gov/pubmed/30266511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.09.021 |
| Oznake: |
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