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Acute Decline in Serum Sclerostin in Response to PTH Infusion in Healthy Men

CONTEXT: Animal models suggest that the osteoblast-stimulating actions of PTH are mediated by acute suppression of sclerostin, an inhibitor of the anabolic Wnt pathway. The immediate physiological changes in serum sclerostin in response to PTH infusion have not been reported in human studies. OBJECT...

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Auteurs principaux: Yu, Elaine W., Kumbhani, Ruchit, Siwila-Sackman, Erica, Leder, Benjamin Z.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205893/
https://ncbi.nlm.nih.gov/pubmed/21865370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1534
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