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Serum Sclerostin Increases in Healthy Adult Men during Bed Rest

CONTEXT: Animal models and human studies suggest that osteocytes regulate the skeleton's response to mechanical unloading in part by an increase in sclerostin. However, few studies have reported changes in serum sclerostin in humans exposed to reduced mechanical loading. OBJECTIVE: We determine...

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Détails bibliographiques
Auteurs principaux: Spatz, J. M., Fields, E. E., Yu, E. W., Pajevic, P. Divieti, Bouxsein, M. L., Sibonga, J. D., Zwart, S. R., Smith, S. M.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431567/
https://ncbi.nlm.nih.gov/pubmed/22767636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2012-1579
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