Acute Decline in Serum Sclerostin in Response to PTH Infusion in Healthy Men

CONTEXT: Animal models suggest that the osteoblast-stimulating actions of PTH are mediated by acute suppression of sclerostin, an inhibitor of the anabolic Wnt pathway. The immediate physiological changes in serum sclerostin in response to PTH infusion have not been reported in human studies. OBJECT...

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Bibliographic Details
Main Authors: Yu, Elaine W., Kumbhani, Ruchit, Siwila-Sackman, Erica, Leder, Benjamin Z.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
Subjects:
JCEM Online: Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205893/
https://ncbi.nlm.nih.gov/pubmed/21865370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-1534
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