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CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication
The HIV-1 genome enters cells inside a shell comprised of capsid (CA) protein. Variation in CA sequence alters HIV-1 infectivity and escape from host restriction factors. However, apart from the Cyclophilin A-binding loop, CA has no known interfaces with which to interact with cellular cofactors. He...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3431306/ https://ncbi.nlm.nih.gov/pubmed/22956906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002896 |
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