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Evolutionary History and Genome Organization of DUF1220 Protein Domains

DUF1220 protein domains exhibit the most extreme human lineage–specific (HLS) copy number increase of any protein coding region in the human genome and have recently been linked to evolutionary and pathological changes in brain size (e.g., 1q21‐associated microcephaly). These findings lend support t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: O’Bleness, Majesta S., Dickens, C. Michael, Dumas, Laura J., Kehrer-Sawatzki, Hildegard, Wyckoff, Gerald J., Sikela, James M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Genetics Society of America 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429928/
https://ncbi.nlm.nih.gov/pubmed/22973535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.003061
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